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Selcia Fragment Library generates hits for GPCR target using TR-FRET

Professor Steven Charlton discusses the use of the Selcia Fragment Library in his oral presentation at the British Pharmacological Society Conference in London on Monday 11th December 2017. In his presentation, entitled ‘Kinetic profiling of fragments at receptors using TR-FRET’,...

Compound Cloud Featured in Latest UK Life Science Industries

BioAscent's Compound Cloud was featured in the latest edition of UK Life Sciences Industry. The full page article outlines Compound Cloud's offerings and describes the growth in online screening compound sales since it was launched a little over a year...

EPAC1 Partial Agonist Identified From Compound Cloud Custom Library

A collaborative screening project involving three Scottish Universities has identified a partial agonist for the cyclic AMP receptor EPAC1 from a Compound Cloud custom library. The research involved academics from Heriot-Watt, Dundee and Glasgow universities, with the results published online by...

Fragment-Based Drug Discovery

With the second ever FDA approval of a fragment derived drug in April, the potential of fragment-based drug design (FBDD) was discussed in September's Nature Reviews Drug Discovery. The article which can be found here addresses the strengths of fragment...